RNA Protein Interaction in Neurons
نویسندگان
چکیده
منابع مشابه
RNA regulons and the RNA-protein interaction network.
Abstract The development of genome-wide analysis tools has prompted global investigation of the gene expression program, revealing highly coordinated control mechanisms that ensure proper spatiotemporal activity of a cell's macromolecular components. With respect to the regulation of RNA transcripts, the concept of RNA regulons, which - by analogy with DNA regulons in bacteria - refers to the c...
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UNLABELLED Although protein-RNA interactions (PRIs) are involved in various important cellular processes, compiled data on PRIs are still limited. This contrasts with protein-protein interactions, which have been intensively recorded in public databases and subjected to network level analysis. Here, we introduce PRD, an online database of PRIs, dispersed across several sources, including scient...
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Protein association networks can be inferred from a range of resources including experimental data, literature mining and computational predictions. These types of evidence are emerging for non-coding RNAs (ncRNAs) as well. However, integration of ncRNAs into protein association networks is challenging due to data heterogeneity. Here, we present a database of ncRNA-RNA and ncRNA-protein interac...
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A protein-protein interaction map of yeast RNA polymerase III.
The structure of the yeast RNA polymerase (pol) III was investigated by exhaustive two-hybrid screening using a library of random genomic fragments fused to the Gal4 activation domain. This procedure allowed us to identify contacts between individual polypeptides, localize the contact domains, and deduce a protein-protein interaction map of the multisubunit enzyme. In all but one case, pol III ...
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ژورنال
عنوان ژورنال: Annual Review of Neuroscience
سال: 2013
ISSN: 0147-006X,1545-4126
DOI: 10.1146/annurev-neuro-062912-114322